GProX

GproX is a powerful and flexible software that analyzes protein structures and functions within a given database. The software allows one to query Uniprot and Ensembl databases for user-defined features.

The application can be valuable to anyone who regularly analyzes proteins and similar datasets. Biology and Chemistry scientists and students will find it very useful as an analysis tool for Proteomics studies. It can also be employed as a teaching aid, more-so since it features highly detailed and accurate graphical representations of the conducted analyses.

For a Science-related program, the software features a surprisingly clean and easy to understand GUI. All navigation is performed via ribbon buttons and users will find that the core functionality of the application can be explored with just a few mouse clicks.

As with any scientific analysis, one must first load source data. This can, in essence, be found inside any file that features a table with a header row. Files can have virtually any extension, as long as the data is valid and a tab or character delimiter is employed.

Upon loading the input protein dataset, the application automatically populates the data table. Users are then free to generate various charts, such as heatmaps and scatter-plots. Simple mathematical and statistical tools can also be employed, for example in order to compute averages or standard deviations.

Enrichment tests and pathway analyses can be conducted, and one of the strong points of this application is that it allows one to query renowned protein databases for organism-specific information. For example, one can use this feature in order to retrieve the transmembrane domain for Homo sapiens. Having this option integrated in the protein analysis suite  is a highly convenient function!

All things considered, GproX is a powerful Proteomics data analyzer that can assist professional users in generating thorough scientific papers.