MAVEN

Being a software solution aimed at constructing ENMS, MAVEN manages to differentiate itself from the competition by providing support for a broad range of Elastic Network Models, thus making them more accessible.

Standard cutoff-based, Spring Tensor, nearest neighbor, as well as mixed resolution models are on the list of supported ENM types.

Being coded in C++, MATLAB, and Perl, MAVEN enables you to get your raw PDB formatted file ready for computations with the help of the “Prepare Files” component, which also allows you to select atoms by type. Besides, converting density maps into PDB files and carrying out spatial coarse-graining should raise no difficulty either, with Help files being integrated in order to streamline the entire process.

Once you have selected an input PDB file as well as the ENM type you are interested in and the proper parameters of the operation, you can run an ENM model. What’s more, quick ENM buttons are available for you to select so that you can run an alpha carbon model once an unprocessed PDB file has been indicated.

Studying B-factors, the anisotropy of motion, fluctuations in internal distances, the correlated motion between two parts of the structure, as well as comparing ENMS can all be done with the help of MAVEN.