Portable UGENE

Gene research has been a fascinating area of research ever since its inception. With the advent of powerful digital tools, it has made steady, but certain progress and has opened up an entire world of possibilities for future development. Portable UGENE is one such program, intended to provide professionals with an adequate and powerful sequences analyzer.

The tool can be applied to a variety of tasks, from common Polymerase Chain Reaction in silico designs to Amino-translations and identical sequences analysis. The application is also able to compute and highlight pair alignment similarities, using either Hirschberg or Smith-Waterman algorithms.

Source information can be loaded from most types of dedicated data containers, including FASTA documents, Genbank repositories or Raw sequence files. Alternatively, one can query the NCBI nucleotide or protein Genbank databases for specific samples. Other supported online search engines are PDB, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and DAS servers.

Once sequence files have been loaded, the program automatically highlights structural differences, making it easy to spot mutations or discrepancies. Color codes, as well as standard notations are employed and the utility also generates gene graphs that can be exported to most common image formats.

Other functions at users' disposal are molecule construction from multiple fragments, HMM3 profile building, dotplots generation, as well as NGS and Sanger data analyses. Researchers can also generate phylogenetic trees, which can be tailor-made to the needs of the current project and exported to SVG format.

One of the great features of this detailed researchers' aid is the ability to customize several functions, including the Workflow. Numerous samples are available and users are free to adjust all elements, including Data Readers, Transcription Factors or HMMER3 Tools. What's more, the tool employs a wide variety of plugins, which can further enhance the power of the analyses.

To conclude, Portable UGENE is a comprehensive Bioinformatics analysis suite that can accommodate even the most demanding needs of professional researchers.