Description
ProfDistS
ProfDistS is a cool app that helps you build big phylogenetic trees using profile distances. It's super user-friendly and has a modern graphical interface. Plus, it can show those trees using some handy third-party tools.
How ProfDistS Works
This app gives you a solid framework for working with phylogenetics by using individual RNA secondary structures. It's based on aligning sequences and structures, and it uses something called Profile Neighbor Joining. You can set up your profiles either manually or let the app do it automatically! Oh, and don't worry; it can also handle protein sequences.
Getting Started
Before diving in, you should make sure that TreeView or NJplot is installed on your computer. While ProfDistS can run without these tools, you'll need them to actually display the phylogenetic trees. You can easily set their paths in the application settings.
Transforming Alignments
When you import alignments into ProfDistS, you have three options for transforming them: profile neighbor joining, RNA bootstrapping, or distance calculation. After loading your file, just pick the method you want from the context menu.
Viewing Phylogenetic Trees
If you're looking to view those phylogenetic trees, ProfDistS will open them in whatever external application you've set up in your settings. So make sure that's all configured right!
Need Help?
If you ever get stuck or need help with any features of the software, just check out the online documentation in the Help menu. There's plenty of info there to guide you through.
If you're ready to give this awesome software a try, download ProfDistS here!
User Reviews for ProfDistS 7
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for ProfDistS
ProfDistS offers a user-friendly experience for constructing large phylogenetic trees using profile distances. Accessible help documentation is a plus.
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for ProfDistS
ProfDistS is an amazing tool for constructing phylogenetic trees! The interface is user-friendly, and the methods it offers are super effective. Highly recommend!
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for ProfDistS
I love using ProfDistS! It's intuitive and powerful for phylogenetic analysis. The ability to work with RNA structures is a game changer. Five stars!
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for ProfDistS
This app has made my research so much easier! ProfDistS's profile distances are fantastic, and the documentation is very helpful. Definitely a must-have!
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for ProfDistS
ProfDistS is top-notch for phylogenetics! The combination of sequence-structure alignments and neighbor joining methods works perfectly for my projects.
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for ProfDistS
I'm really impressed with ProfDistS! It simplifies complex phylogenetic tree constructions and integrates well with external tools. A solid five-star app!
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for ProfDistS
Fantastic application! ProfDistS has greatly improved my workflow in constructing large phylogenetic trees, making it easy to visualize results. Highly recommended!