What is ProfDistS?

ProfDistS

ProfDistS is a cool app that helps you build big phylogenetic trees using profile distances. It's super user-friendly and has a modern graphical interface. Plus, it can show those trees using some handy third-party tools.

How ProfDistS Works

This app gives you a solid framework for working with phylogenetics by using individual RNA secondary structures. It's based on aligning sequences and structures, and it uses something called Profile Neighbor Joining. You can set up your profiles either manually or let the app do it automatically! Oh, and don't worry; it can also handle protein sequences.

Getting Started

Before diving in, you should make sure that TreeView or NJplot is installed on your computer. While ProfDistS can run without these tools, you'll need them to actually display the phylogenetic trees. You can easily set their paths in the application settings.

Transforming Alignments

When you import alignments into ProfDistS, you have three options for transforming them: profile neighbor joining, RNA bootstrapping, or distance calculation. After loading your file, just pick the method you want from the context menu.

Viewing Phylogenetic Trees

If you're looking to view those phylogenetic trees, ProfDistS will open them in whatever external application you've set up in your settings. So make sure that's all configured right!

Need Help?

If you ever get stuck or need help with any features of the software, just check out the online documentation in the Help menu. There's plenty of info there to guide you through.

If you're ready to give this awesome software a try, download ProfDistS here!

How Download Works

Go to the Softpas website, press the 'Downloads' button, and pick the app you want to download and install—easy and fast!